Do I need clamps to install this, and what size?

You'll need hose clamps on both ends. Measure your existing tubing OD — typically 2.75" on the inlet side and 3.00" on the outlet side. Worm-drive or T-bolt clamps work best; torque per your vehicle's service manual or tighten until the hose seals without over-compressing the silicone.

Can I use this on a turbo boost line or does it need to be coolant-only?

This hose works for both boost and coolant applications. The 3-ply weave handles positive pressure from turbo or supercharger systems as well as the thermal cycling of cooling circuits. Confirm your peak boost PSI matches silicone's pressure rating before installation.

Should I clean or prep the inside of the hose before connecting it?

Rinse the interior with clean water or compressed air to remove any manufacturing dust or debris, especially if you're running this on a boost line where particles can clog intercooler cores. For coolant lines, flush if transitioning from an old steel hose to eliminate rust particles.