Nanog P8 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2895-50, ES2895-100

Citations, Manuals and MSDS Available upon request.

Background: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009],

Alternate Name: NANOGP8; Putative homeobox protein NANOGP8

Source: Rabbit

Applications: WB; IF; ELISA; IHC

Dilution: WB 1:500-2000; IF/ICC 1:50-200; ELISA 1:2000-20000; IHC-p 1:50-200

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human NANOGP8. AA range:51-100

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 35kD

Human Gene ID: 388112

Human SWISS Prot NO: Q6NSW7

Subcellular Location: Nucleus

Research Use Only