Advanced Retinal Night Serum for Wrinkles, Firmness & Visible Skin Renewal

Dermatologist-recommended ISDIN Retinal Advanced is a powerful nighttime treatment formulated with retinaldehyde (retinal), an advanced vitamin A derivative known for delivering visible anti-aging results while remaining more tolerable than traditional retinoid therapies. This innovative overnight serum helps improve the appearance of fine lines, wrinkles, uneven texture, and loss of firmness while supporting smoother, brighter, and younger-looking skin.

Featuring ISDIN's specialized retinal delivery technology and soothing ingredients, Retinal Advanced helps accelerate skin renewal while minimizing the dryness and irritation commonly associated with retinoid use. The lightweight serum absorbs quickly and works overnight to promote a healthier, more rejuvenated complexion.

Best For

• Fine lines and wrinkles

• Loss of firmness and elasticity

• Uneven skin texture

• Dull or aging skin

• Healthy aging skincare routines

• Retinoid users seeking advanced results

Why We Love It

• Powered by advanced retinal technology

• Helps visibly reduce wrinkles and fine lines

• Supports firmer, smoother-looking skin

• Promotes overnight skin renewal

• Designed for improved tolerability compared to traditional retinoids

Key Benefits

• Helps reduce the appearance of fine lines and wrinkles

• Improves skin texture and smoothness

• Supports firmer, more youthful-looking skin

• Enhances overall skin radiance

• Encourages healthy cell turnover

• Promotes visible skin rejuvenation with continued use

Why Dermatologists Recommend ISDIN Retinal Advanced

Our dermatology team recommends ISDIN Retinal Advanced for patients seeking a next-generation retinoid treatment that delivers significant anti-aging benefits while supporting skin comfort. Retinaldehyde is one of the most effective non-prescription vitamin A derivatives available and helps improve multiple signs of aging, including wrinkles, texture irregularities, and loss of firmness.

Key Ingredients

Retinaldehyde (Retinal)

An advanced vitamin A derivative that helps accelerate skin renewal, improve the appearance of wrinkles, and support smoother, firmer-looking skin.

Specialized Retinal Delivery System

Helps optimize retinal stability and effectiveness while improving skin tolerability.

Soothing Complex

Helps minimize dryness and irritation commonly associated with retinoid use.

Hydrating Ingredients

Support skin moisture levels and barrier function during the skin renewal process.

Antioxidant Support

Helps defend against environmental stressors that contribute to premature aging.

How to Use

Apply a pea-sized amount to clean, dry skin in the evening. Avoid direct contact with the eyes and lips. Begin using 2–3 nights per week and gradually increase frequency as tolerated. Follow with a moisturizer if needed. Use sunscreen daily while using retinal products.

What to Expect

Skin may appear smoother and more radiant within the first several weeks of use. With continued use, the appearance of fine lines, wrinkles, uneven texture, and loss of firmness may visibly improve, revealing a healthier, more youthful-looking complexion.

Derm Tip

Our dermatology team recommends introducing ISDIN Retinal Advanced gradually, especially for those new to retinoids. Pair with a hydrating moisturizer and broad-spectrum sunscreen daily to maximize results and support skin barrier health.

FAQs

What does ISDIN Retinal Advanced help with?

It helps improve the appearance of fine lines, wrinkles, uneven texture, dullness, and loss of firmness while promoting overall skin renewal.

What is retinaldehyde?

Retinaldehyde (retinal) is an advanced vitamin A derivative that works faster than retinol while helping improve visible signs of aging and skin texture.

Is ISDIN Retinal Advanced stronger than retinol?

Yes. Retinal is generally considered more potent than traditional retinol because it requires fewer conversion steps within the skin to become active.

Can I use ISDIN Retinal Advanced every night?

Most users can gradually work up to nightly use, but it is recommended to start slowly and increase frequency as tolerated.

Do I need sunscreen while using ISDIN Retinal Advanced?

Yes. Daily sunscreen use is essential when using retinal or other retinoid products to help protect the skin and maintain results.

SIZE: 50 ml / 1.7 Fl. Oz