Description Why is Pro-Gest® Cream so trusted? Maybe because it's been the leader since 1978. For 35 years, women have relied on Pro-Gest® for support at midlife. Our Single-Use size contains 48 single-use packets, designed for convenience. There’s no guesswork, and they’re easy to take along with you on-the-go. Each packet contains ¼ teaspoon of cream. Pro-Gest® Cream contains 450 mg of USP Progesterone per ounce (20 mg per 1/4 teaspoon). Our progesterone comes from the Mexican Wild Yam and is converted to pure USP Progesterone (meeting the standards of the United States Pharmacopeia for strength, purity and quality).