Advantages

Skin closure

• Wound closure in one minute [1, 2, 3, 4]
• Significant less pain than suture materials [5]
• Effective microbial barrier [6, 7, 8]
• Storage at room temperature <22º [9]
• High level of patient and physician satisfaction [2, 7, 10, 11, 12]
• Save time and costs [1, 2, 3, 4, 5, 10, 12]
• Only one layer is needed [4, 8]
• Histoacryl® can be used for closure of endoscopic incisions [8, 13]

Sclerotherapy

• For bleeding and non-bleeding varices [14, 15, 16, 17, 18, 19]
• Combined therapy with Histoacryl® and conventional sclerosation therapy is possible] [14, 15, 17, 20]
• Final hemostasis is achieved in >90% of cases [14, 15, 16, 17, 18, 19]
• Lower rebleeding rate than with band ligation [14, 15, 18, 20]

Mesh fixation

• Non-invasive method reported to be better tolerated by the patient than traditional fixation methods [22, 23, 24, 25, 26]
• Stand-alone fixation method in different hernia repair techniques [22, 23, 24, 25, 26]
• Comparable recurrence rate than with traditional fixation methods [23, 24, 25, 26]
• Low intra- and postoperative morbidity [24, 26]
• Reduced risk of post-operative chronic pain compared to traditional fixation methods [23, 24, 25, 26]
• Decreased surgery time compared to traditional fixation methods [23, 25]
• Good biocompatibility and in vivo tolerance [23, 24, 25, 26, 27]