Dermo Guna Facial Serum is a fluid, silky anti-wrinkle treatment developed by Guna research to reduce the signs of aging on the skin. It improves skin firmness, tone, and elasticity. It reduces signs of skin fatigue and the visibility of wrinkles ^.In addition to Dermacollagen Neorland ^® analyzed for the presence of exosomes, it contains:

Contains:

• Vitamin E : is the skin's primary topical antioxidant .
• Rosa Centifolia flower water : has calming and soothing properties and an antioxidant activity
• Vitamin C (Ascorbyl Tetraisopalmitate) : A natural antioxidant that protects the skin from UV damage and has a depigmenting effect on hyperpigmented skin spots. This molecule has limitations in terms of formulation stability and skin permeability. This is why ascorbyl tetraisopalmitate (VC-IP), a lipophilic precursor of vitamin C, was used. It is converted into vitamin C through an enzymatic reaction, thereby exerting its effects.

  1. VC-IP reduces the production of IL-1α and PGE2 in keratinocytes irradiated by UV-B rays, modulating melanogenesis: these molecules are involved in the proliferation of melanocytes and in the increase in the expression of tyrosinase, a key enzyme in melanin synthesis;

  2. VC-IP is able to reduce the damage caused by UV rays and ROS, with a decrease in intracellular H2O2 levels. ⁹

  Vitamin C is essential for collagen synthesis: it is a necessary cofactor for the enzymatic activity of prolyl hydroxylase and lysyl hydroxylase.

Clinical instrumental study conducted on 20 women aged between 40 and 65.

The study analyzed:

1. reduction of wrinkle area ;
2. increased skin elasticity ;
3. improving skin firmness ;
4. the improvement of the skin fatigue index .

The results obtained demonstrated that Dermo guna anti-wrinkle facial serum is effective in improving the firmness, tone and elasticity of the skin, reducing the signs of skin fatigue and, in particular, the visibility of wrinkles.

The women interviewed gave a rating of pleasantness and positive effect on the skin in conjunction with the application of Dermo guna anti-wrinkle facial serum treatment .

Ingredients

Aqua, Rosa Centifolia Flower Water, Coco Caprylate/Caprate, Ethylhexyl Stearate, Glycerin, Ascorbyl Tetraisopalmitate, Arachidyl Alcohol, Hydrolyzed Collagen, Behenyl Alcohol, Hydroxyethylcellulose, Hydroxyacetophenone, Arachidyl Glucoside, Caprylyl Glycol, 1,2-Hexanediol, Parfum, Rosa Canina Fruit Extract, Sodium Hydroxyde, Citric Acid, Potassium Sorbate, Sodium Benzoate, Lecithin, Tocopherol, Ascorbyl Palmitate, Acetyl Cedrene*, Hexamethylindanopyran*, Linalyl Acetate*, Terpineol*, Tetramethyl Acetyloctahydronaphthalenes*.
* allergenic substances Reg. 1223/2009/CE not used as such but naturally present in the ingredients used in the formulation.

Instructions

Apply morning and evening to a cleansed face. Massage with long, gentle strokes to promote absorption.